Berberine: Health or hype?

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When looking at weight loss, the benefit of berberine appears to be from activating an enzyme inside cells called AMP-activated protein kinase (AMPK).

By Mike Ventresca, Vital Choice Healthstore

Over the past few months, berberine has exploded across social media as the next weight-loss miracle pill, with some calling it “Nature’s Ozempic.” While I think these weight-loss claims are exaggerated, it is true that berberine has been shown to provide support for a variety of conditions, including irritable bowel syndrome, polycystic ovary syndrome, high cholesterol, heart disease, type 2 diabetes and, yes, weight management. Today, let’s look at two of these, blood sugar and weight loss.

Mike Ventresca

Berberine has been extensively studied for its ability to lower blood sugar in clinical trials. It appears to work in several different ways, including decreasing insulin resistance (effectively making the body’s insulin more effective) and increasing glycolysis, the process of breaking down sugar in cells. According to research, when compared to common medications like metformin, berberine was as effective as drugs, but with no significant side effects.

When looking at weight loss, the benefit appears to be from activating an enzyme inside cells called AMP-activated protein kinase (AMPK). AMPK plays a key role in regulating metabolism and energy levels and is found in cells throughout the body. While more studies are needed, preliminary studies show promise. One study from 2012 found that after taking berberine for 12 weeks, participants lost an average of five pounds, while other studies found reductions in body weight, body mass index and belly fat.

If you’re interested in trying berberine, one excellent option is Vital Choice’s Berberine. It provides the same dosage found in many studies. Another great option is Enzymedica’s new Berberine Phytosome, offering 9.6-times better bioavailability.

Mike Ventresca is the owner of Vital Choice Health Store, 9243 Sprague Road in North Royalton’s Timber Ridge Plaza. Call 440-885-9505 or visit This information is not intended to diagnose, treat, cure, or prevent any disease.